81 MLB Players debut on July 16
| # | Player | debut Date |
|---|---|---|
| 1. | Trey Amburgey | 7/16/2021 |
| 2. | Buddy Baumann | 7/16/2016 |
| 3. | Dave Beard | 7/16/1980 |
| 4. | Ralph Bell | 7/16/1912 |
| 5. | Lance Berkman | 7/16/1999 |
| 6. | Walter Bernhardt | 7/16/1918 |
| 7. | Rich Bordi | 7/16/1980 |
| 8. | Mark Buehrle | 7/16/2000 |
| 9. | Lorenzo Cain | 7/16/2010 |
| 10. | Ken Caminiti | 7/16/1987 |
| 11. | Pat Capri | 7/16/1944 |
| 12. | Harry Child | 7/16/1930 |
| 13. | Bob Chlupsa | 7/16/1970 |
| 14. | Jim Clark | 7/16/1971 |
| 15. | Howie Clark | 7/16/2002 |
| 16. | Mike Coolbaugh | 7/16/2001 |
| 17. | Phil Coridan | 7/16/1884 |
| 18. | Dan Cotter | 7/16/1890 |
| 19. | George Curry | 7/16/1911 |
| 20. | George Davis | 7/16/1912 |
| 21. | Rick DeHart | 7/16/1997 |
| 22. | Pat Duncan | 7/16/1915 |
| 23. | Don Durham | 7/16/1972 |
| 24. | Ben Ellis | 7/16/1896 |
| 25. | Bobby Etheridge | 7/16/1967 |
| 26. | Dana Eveland | 7/16/2005 |
| 27. | Pete Falsey | 7/16/1914 |
| 28. | Hank Gehring | 7/16/1907 |
| 29. | Chappie Geygan | 7/16/1924 |
| 30. | Erik Gonzalez | 7/16/2016 |
| 31. | Tom Gorman | 7/16/1952 |
| 32. | Chris Hammond | 7/16/1990 |
| 33. | Garry Hancock | 7/16/1978 |
| 34. | Hub Hart | 7/16/1905 |
| 35. | Gary Haught | 7/16/1997 |
| 36. | Tommy Hinzo | 7/16/1987 |
| 37. | Don Hood | 7/16/1973 |
| 38. | Mike Jacobs | 7/16/1902 |
| 39. | Bucky Jacobsen | 7/16/2004 |
| 40. | Abe Johnson | 7/16/1893 |
| 41. | Adam Johnson | 7/16/2001 |
| 42. | Tim Kubinski | 7/16/1997 |
| 43. | Otis Lambeth | 7/16/1916 |
| 44. | Pat Larkin | 7/16/1983 |
| 45. | Jensen Lewis | 7/16/2007 |
| 46. | Harry Little | 7/16/1877 |
| 47. | Ryan Long | 7/16/1997 |
| 48. | Willie Lozado | 7/16/1984 |
| 49. | Jhan Marinez | 7/16/2010 |
| 50. | Howie McFarland | 7/16/1945 |
| 51. | Al McLean | 7/16/1935 |
| 52. | George Metkovich | 7/16/1943 |
| 53. | Max Meyer | 7/16/2022 |
| 54. | Otto Miller | 7/16/1910 |
| 55. | Joe Millette | 7/16/1992 |
| 56. | Wayne Nordhagen | 7/16/1976 |
| 57. | John O'Donnell | 7/16/1884 |
| 58. | Fred Ostendorf | 7/16/1914 |
| 59. | Juan Padilla | 7/16/2004 |
| 60. | Hoy Park | 7/16/2021 |
| 61. | Adam Pettyjohn | 7/16/2001 |
| 62. | Dan Reichert | 7/16/1999 |
| 63. | Ed Romero | 7/16/1977 |
| 64. | Pedro Santana | 7/16/2001 |
| 65. | Chad Santos | 7/16/2006 |
| 66. | Art Schallock | 7/16/1951 |
| 67. | Scott | 7/16/1884 |
| 68. | Kal Segrist | 7/16/1952 |
| 69. | Bob Shawkey | 7/16/1913 |
| 70. | George Sherrill | 7/16/2004 |
| 71. | Marcelino Solis | 7/16/1958 |
| 72. | Ryan Spilborghs | 7/16/2005 |
| 73. | Joe Sprinz | 7/16/1930 |
| 74. | Ray Steineder | 7/16/1923 |
| 75. | Lee Stevens | 7/16/1990 |
| 76. | Bill Stoneman | 7/16/1967 |
| 77. | Bill Strickland | 7/16/1937 |
| 78. | Ted Sullivan | 7/16/1884 |
| 79. | Chris Van Cuyk | 7/16/1950 |
| 80. | Bill Wagner | 7/16/1914 |
| 81. | George Williams | 7/16/1961 |
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