115 MLB Players debut on April 28
| # | Player | debut Date |
|---|---|---|
| 1. | Nolan Arenado | 4/28/2013 |
| 2. | Henry Austin | 4/28/1873 |
| 3. | Bock Baker | 4/28/1901 |
| 4. | Jack Baldschun | 4/28/1961 |
| 5. | Dave Bartosch | 4/28/1945 |
| 6. | Joe Bean | 4/28/1902 |
| 7. | Clarence Blair | 4/28/1929 |
| 8. | Ben Blomdahl | 4/28/1995 |
| 9. | Cy Bowen | 4/28/1896 |
| 10. | Marshall Boze | 4/28/1996 |
| 11. | George Bradley | 4/28/1946 |
| 12. | Theodore Breitenstein | 4/28/1891 |
| 13. | Scott Brow | 4/28/1993 |
| 14. | Leon Cadore | 4/28/1915 |
| 15. | Les Cain | 4/28/1968 |
| 16. | Eric Cammack | 4/28/2000 |
| 17. | Hugh Campbell | 4/28/1873 |
| 18. | Michael Campbell | 4/28/1873 |
| 19. | Jay Canizaro | 4/28/1996 |
| 20. | Don Carlsen | 4/28/1948 |
| 21. | Chuck Carr | 4/28/1990 |
| 22. | Alberto Castillo | 4/28/2008 |
| 23. | Dick Coffman | 4/28/1927 |
| 24. | A. J. Cole | 4/28/2015 |
| 25. | Bob Collins | 4/28/1940 |
| 26. | Connie Creeden | 4/28/1943 |
| 27. | Felipe Crespo | 4/28/1996 |
| 28. | George Darby | 4/28/1893 |
| 29. | Mark DeJohn | 4/28/1982 |
| 30. | Eddie Delker | 4/28/1929 |
| 31. | Con Dempsey | 4/28/1951 |
| 32. | John Ely | 4/28/2010 |
| 33. | Del Ennis | 4/28/1946 |
| 34. | Jewel Ens | 4/28/1922 |
| 35. | John Farrow | 4/28/1873 |
| 36. | Jack Fifield | 4/28/1897 |
| 37. | Chad Fonville | 4/28/1995 |
| 38. | Russ Ford | 4/28/1909 |
| 39. | Kevin Frandsen | 4/28/2006 |
| 40. | Bob Friend | 4/28/1951 |
| 41. | Greg Garcia | 4/28/2014 |
| 42. | Ned Garver | 4/28/1948 |
| 43. | Jim Geddes | 4/28/1972 |
| 44. | Chris Getz | 4/28/2008 |
| 45. | Luis Gomez | 4/28/1974 |
| 46. | Severino Gonzalez | 4/28/2015 |
| 47. | Nelson Greene | 4/28/1924 |
| 48. | Randal Grichuk | 4/28/2014 |
| 49. | Mark Grudzielanek | 4/28/1995 |
| 50. | Ralph Hamner | 4/28/1946 |
| 51. | Greg Hansell | 4/28/1995 |
| 52. | Larry Hardy | 4/28/1974 |
| 53. | Bryce Harper | 4/28/2012 |
| 54. | Roy Hartsfield | 4/28/1950 |
| 55. | Clem Hausmann | 4/28/1944 |
| 56. | Tyler Holton | 4/28/2022 |
| 57. | Ben Howard | 4/28/2002 |
| 58. | Luke Hughes | 4/28/2010 |
| 59. | Daryl Irvine | 4/28/1990 |
| 60. | Ernie Johnson | 4/28/1950 |
| 61. | Bill Karlon | 4/28/1930 |
| 62. | John Keefe | 4/28/1890 |
| 63. | Bill Koski | 4/28/1951 |
| 64. | Jerry Kutzler | 4/28/1990 |
| 65. | Ryan Langerhans | 4/28/2002 |
| 66. | Ben Laughlin | 4/28/1873 |
| 67. | Derrek Lee | 4/28/1997 |
| 68. | Mark Leiter | 4/28/2017 |
| 69. | Rommie Lewis | 4/28/2010 |
| 70. | Bob Lipski | 4/28/1963 |
| 71. | Urbano Lugo | 4/28/1985 |
| 72. | Sean Maloney | 4/28/1997 |
| 73. | Joe Martin | 4/28/1903 |
| 74. | Clyde McCullough | 4/28/1940 |
| 75. | Lou McEvoy | 4/28/1930 |
| 76. | Luis Montanez | 4/28/2008 |
| 77. | Glen Moulder | 4/28/1946 |
| 78. | Joe Murphy | 4/28/1886 |
| 79. | Les Nunamaker | 4/28/1911 |
| 80. | Trevor Oaks | 4/28/2018 |
| 81. | Bob Oldis | 4/28/1953 |
| 82. | Hunter Pence | 4/28/2007 |
| 83. | Shannon Penn | 4/28/1995 |
| 84. | Ricky Pickett | 4/28/1998 |
| 85. | Joe Pignatano | 4/28/1957 |
| 86. | Earl Rapp | 4/28/1949 |
| 87. | Lew Riggs | 4/28/1934 |
| 88. | Saul Rogovin | 4/28/1949 |
| 89. | Rick Sawyer | 4/28/1974 |
| 90. | Curt Schmidt | 4/28/1995 |
| 91. | Dave Schmidt | 4/28/1981 |
| 92. | Jason Schmidt | 4/28/1995 |
| 93. | Doc Sechrist | 4/28/1899 |
| 94. | Frank Secory | 4/28/1940 |
| 95. | Dick Sipek | 4/28/1945 |
| 96. | D. J. Snelten | 4/28/2018 |
| 97. | Earl Snyder | 4/28/2002 |
| 98. | Steve Sparks | 4/28/1995 |
| 99. | Todd Steverson | 4/28/1995 |
| 100. | Franklin Stubbs | 4/28/1984 |
| 101. | Harry Swan | 4/28/1914 |
| 102. | Rich Thompson | 4/28/1985 |
| 103. | Thomas Tinney | 4/28/1884 |
| 104. | Steven Tolleson | 4/28/2010 |
| 105. | Andy Tomasic | 4/28/1949 |
| 106. | Rene Tosoni | 4/28/2011 |
| 107. | Ron Villone | 4/28/1995 |
| 108. | Jimmy Wacker | 4/28/1909 |
| 109. | Dixie Walker | 4/28/1931 |
| 110. | Rube Ward | 4/28/1902 |
| 111. | Les Willis | 4/28/1947 |
| 112. | Bobby Wilson | 4/28/2008 |
| 113. | Gary Wilson | 4/28/1995 |
| 114. | Ken Wood | 4/28/1948 |
| 115. | Favel Wordsworth | 4/28/1873 |
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