91 MLB Players debut in 1959
| # | Player | debut Date |
|---|---|---|
| 1. | George Altman | 4/11/1959 |
| 2. | Sparky Anderson | 4/10/1959 |
| 3. | Rudy Arias | 4/10/1959 |
| 4. | Jim Bailey | 9/10/1959 |
| 5. | Jim Baxes | 4/11/1959 |
| 6. | Gary Blaylock | 4/10/1959 |
| 7. | Marshall Bridges | 6/17/1959 |
| 8. | Ernie Broglio | 4/11/1959 |
| 9. | Jim Bronstad | 6/7/1959 |
| 10. | Bob Bruce | 9/14/1959 |
| 11. | Duke Carmel | 9/10/1959 |
| 12. | Cam Carreon | 9/27/1959 |
| 13. | Joe Christopher | 5/26/1959 |
| 14. | Gordy Coleman | 9/19/1959 |
| 15. | Cliff Cook | 9/9/1959 |
| 16. | Chuck Cottier | 4/17/1959 |
| 17. | Mike Cuellar | 4/18/1959 |
| 18. | Jerry Davie | 4/14/1959 |
| 19. | Tommy Davis | 9/22/1959 |
| 20. | Steve Demeter | 7/29/1959 |
| 21. | Don Dillard | 4/24/1959 |
| 22. | Dan Dobbek | 9/9/1959 |
| 23. | Ed Donnelly | 8/1/1959 |
| 24. | Bob Duliba | 8/11/1959 |
| 25. | Don Eaddy | 4/24/1959 |
| 26. | Eddie Fisher | 6/22/1959 |
| 27. | Jack Fisher | 4/14/1959 |
| 28. | Mark Freeman | 4/18/1959 |
| 29. | John Gabler | 9/18/1959 |
| 30. | Bob Gibson | 4/15/1959 |
| 31. | Bob Giggie | 4/18/1959 |
| 32. | Buddy Gilbert | 9/9/1959 |
| 33. | Don Gile | 9/25/1959 |
| 34. | Eli Grba | 7/10/1959 |
| 35. | Pumpsie Green | 7/21/1959 |
| 36. | Fred Green | 4/15/1959 |
| 37. | Bob Hartman | 4/26/1959 |
| 38. | Joe Hicks | 9/18/1959 |
| 39. | Tom Hughes | 9/13/1959 |
| 40. | Ken Hunt | 9/10/1959 |
| 41. | Al Jackson | 5/31/1959 |
| 42. | Ben Johnson | 9/6/1959 |
| 43. | Jim Kaat | 8/2/1959 |
| 44. | Ed Keegan | 8/24/1959 |
| 45. | Evans Killeen | 9/7/1959 |
| 46. | Jack Kralick | 4/15/1959 |
| 47. | Marty Kutyna | 9/19/1959 |
| 48. | Gene Leek | 4/22/1959 |
| 49. | Bobby Locke | 6/18/1959 |
| 50. | Jim Mahoney | 7/28/1959 |
| 51. | Jerry Mallett | 9/19/1959 |
| 52. | J. C. Martin | 9/10/1959 |
| 53. | Lee Maye | 7/17/1959 |
| 54. | Tom McAvoy | 9/27/1959 |
| 55. | Ken McBride | 8/4/1959 |
| 56. | Roger McCardell | 5/8/1959 |
| 57. | Tim McCarver | 9/10/1959 |
| 58. | Willie McCovey | 7/30/1959 |
| 59. | Joe Morgan | 4/14/1959 |
| 60. | Howie Nunn | 4/11/1959 |
| 61. | Jim O'Rourke | 6/16/1959 |
| 62. | Gene Oliver | 6/6/1959 |
| 63. | Jose Pagan | 8/4/1959 |
| 64. | Jim Perry | 4/23/1959 |
| 65. | Gary Peters | 9/10/1959 |
| 66. | Jim Proctor | 9/14/1959 |
| 67. | Claude Raymond | 4/15/1959 |
| 68. | Marshall Renfroe | 9/27/1959 |
| 69. | Dick Ricketts | 6/14/1959 |
| 70. | Bob Saverine | 9/12/1959 |
| 71. | Joe Schaffernoth | 4/15/1959 |
| 72. | Wally Shannon | 7/9/1959 |
| 73. | Norm Sherry | 4/12/1959 |
| 74. | Barry Shetrone | 7/27/1959 |
| 75. | Ron Shoop | 8/22/1959 |
| 76. | Chris Short | 4/19/1959 |
| 77. | Russ Snyder | 4/18/1959 |
| 78. | Gene Snyder | 4/26/1959 |
| 79. | Al Spangler | 9/16/1959 |
| 80. | Joe Stanka | 9/2/1959 |
| 81. | Wes Stock | 4/19/1959 |
| 82. | Jake Striker | 9/25/1959 |
| 83. | Jim Umbricht | 9/26/1959 |
| 84. | Fred Valentine | 9/7/1959 |
| 85. | Zoilo Versalles | 8/1/1959 |
| 86. | Ray Webster | 4/17/1959 |
| 87. | Billy Williams | 8/6/1959 |
| 88. | Ted Wills | 5/24/1959 |
| 89. | Maury Wills | 6/6/1959 |
| 90. | Earl Wilson | 7/28/1959 |
| 91. | Gordie Windhorn | 9/10/1959 |
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