88 MLB Players debut on September 28
| # | Player | debut Date |
|---|---|---|
| 1. | Larry Battam | 9/28/1895 |
| 2. | George Batten | 9/28/1912 |
| 3. | Desmond Beatty | 9/28/1914 |
| 4. | Johnny Beazley | 9/28/1941 |
| 5. | Elmer Bliss | 9/28/1903 |
| 6. | Don Bollweg | 9/28/1950 |
| 7. | Lou Brissie | 9/28/1947 |
| 8. | Fritz Buelow | 9/28/1899 |
| 9. | John Butler | 9/28/1901 |
| 10. | Bob Chipman | 9/28/1941 |
| 11. | Jim Cockman | 9/28/1905 |
| 12. | Joe Coleman | 9/28/1965 |
| 13. | Toots Coyne | 9/28/1914 |
| 14. | Buddy Crump | 9/28/1924 |
| 15. | John Dagenhard | 9/28/1943 |
| 16. | Hooks Dauss | 9/28/1912 |
| 17. | Dizzy Dean | 9/28/1930 |
| 18. | Rod Dedeaux | 9/28/1935 |
| 19. | Steve Dillard | 9/28/1975 |
| 20. | Sammy Esposito | 9/28/1952 |
| 21. | Terry Felton | 9/28/1979 |
| 22. | John Fitzgerald | 9/28/1958 |
| 23. | Lew Flick | 9/28/1943 |
| 24. | Mike Gonzalez | 9/28/1912 |
| 25. | Ted Goulait | 9/28/1912 |
| 26. | Shawn Green | 9/28/1993 |
| 27. | Kent Greenfield | 9/28/1924 |
| 28. | Oscar Grimes | 9/28/1938 |
| 29. | Sig Gryska | 9/28/1938 |
| 30. | Sam Harshaney | 9/28/1937 |
| 31. | Marc Hill | 9/28/1973 |
| 32. | Bill Hughes | 9/28/1884 |
| 33. | Chuck James | 9/28/2005 |
| 34. | Slats Jordan | 9/28/1901 |
| 35. | Mike Judd | 9/28/1997 |
| 36. | George Kell | 9/28/1943 |
| 37. | Silver King | 9/28/1886 |
| 38. | Jay Kirke | 9/28/1910 |
| 39. | George Knight | 9/28/1875 |
| 40. | Mickey Kreitner | 9/28/1943 |
| 41. | Gary Lance | 9/28/1977 |
| 42. | Bill Landis | 9/28/1963 |
| 43. | Don Landrum | 9/28/1957 |
| 44. | Tommy Leach | 9/28/1898 |
| 45. | Dutch Levsen | 9/28/1923 |
| 46. | Charlie Lindstrom | 9/28/1958 |
| 47. | Ray Lucas | 9/28/1929 |
| 48. | Duster Mails | 9/28/1915 |
| 49. | Doc Marshall | 9/28/1929 |
| 50. | Rube Marshall | 9/28/1912 |
| 51. | Lou Marson | 9/28/2008 |
| 52. | Henry Mathewson | 9/28/1906 |
| 53. | Wally Mayer | 9/28/1911 |
| 54. | Marty McHale | 9/28/1910 |
| 55. | George McNamara | 9/28/1922 |
| 56. | Russ Meers | 9/28/1941 |
| 57. | Andy Merchant | 9/28/1975 |
| 58. | Rod Miller | 9/28/1957 |
| 59. | Gene Moore | 9/28/1909 |
| 60. | Johnny Morrison | 9/28/1920 |
| 61. | Ivan Murrell | 9/28/1963 |
| 62. | Riley O'Brien | 9/28/2021 |
| 63. | Roy Parmelee | 9/28/1929 |
| 64. | Andy Pratt | 9/28/2002 |
| 65. | Eddie Quick | 9/28/1903 |
| 66. | Morrie Rath | 9/28/1909 |
| 67. | Dustin Richardson | 9/28/2009 |
| 68. | Edwin Rodriguez | 9/28/1982 |
| 69. | Kim Seaman | 9/28/1979 |
| 70. | Carroll Sembera | 9/28/1965 |
| 71. | Frank Seward | 9/28/1943 |
| 72. | Al Shaw | 9/28/1907 |
| 73. | Duke Shirey | 9/28/1920 |
| 74. | Curt Simmons | 9/28/1947 |
| 75. | Jack Slattery | 9/28/1901 |
| 76. | Klondike Smith | 9/28/1912 |
| 77. | Pete Sweeney | 9/28/1888 |
| 78. | Buck Sweeney | 9/28/1914 |
| 79. | Fred Talbot | 9/28/1963 |
| 80. | Jim Tennant | 9/28/1929 |
| 81. | Jake Volz | 9/28/1901 |
| 82. | Bruce Von Hoff | 9/28/1965 |
| 83. | Jack Wanner | 9/28/1909 |
| 84. | Dick West | 9/28/1938 |
| 85. | Woody Wheaton | 9/28/1943 |
| 86. | Fred Worden | 9/28/1914 |
| 87. | Dom Zanni | 9/28/1958 |
| 88. | Joe Zapustas | 9/28/1933 |
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